The Mel Robbins Podcast
The Mel Robbins Podcast
April 27, 2026

Nervous System Reset: Do THIS Every Day to Rewire Your Brain From Stress and Anxiety

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Quick Read

Dr. Nadine Burke Harris reveals how childhood trauma biologically rewires our stress response, leading to adult health issues, and offers a science-backed 'buffering' playbook to heal and regain control.
Trauma is your body's biological response to overwhelming stress, not just the event itself.
Adverse Childhood Experiences (ACEs) can permanently wire an overactive stress response, affecting adult health and behavior.
Intentional 'buffering' through self-care, relationships, and therapy can rewire your biology and heal past trauma.

Summary

Dr. Nadine Burke Harris, a leading expert in trauma science and public health, explains that trauma is not the stressor itself, but the body's biological response to overwhelming stress. She details how adverse childhood experiences (ACEs) can permanently alter the body's stress response, leading to chronic health issues like heart disease, autoimmune disorders, and mental health challenges, even if the individual doesn't consciously remember the events. Dr. Burke Harris introduces the concept of 'buffering'—intentional interventions and supportive relationships that help re-regulate the nervous system. Using the 'teeter-totter' analogy, she illustrates how early adversity shifts the body's baseline, requiring significant buffering to restore balance. She emphasizes that while willpower often fails against a biologically wired stress response, practices like mindfulness, exercise, healthy relationships, and therapies like EMDR can create 'corrective experiences' that literally change the body's biology and allow for healing.
Understanding that trauma is a biological response, not just an event, empowers individuals to address chronic stress and its pervasive impact on health, relationships, and daily functioning. This episode provides a clear framework for identifying the roots of an overactive stress response and offers actionable, evidence-based strategies to re-regulate the nervous system, fostering greater well-being, healthier relationships, and a sense of control over one's life.

Takeaways

  • Trauma is defined as the body's biological response to overwhelming stress, not the stressor itself.
  • Early childhood experiences, even those not consciously remembered, can profoundly shape and wire the stress response for life.
  • The Adverse Childhood Experiences (ACEs) study identified 10 categories of childhood adversity linked to increased risk of chronic diseases and mental health issues in adulthood.
  • An overactive stress response leads to chronic inflammation and can manifest as physical ailments (headaches, autoimmune disease) or behavioral issues (reactivity, procrastination).
  • Buffering involves interventions like safe relationships, self-regulation practices (mindfulness, exercise), and therapy to re-regulate the body's stress response.
  • The 'teeter-totter' analogy illustrates how early adversity shifts the body's baseline, requiring more buffering to achieve balance.
  • Corrective experiences, often facilitated by therapy like EMDR, can literally change epigenetic markers and rewire the brain's stress response.
  • Willpower and motivation are often ineffective against a biologically overactive nervous system; understanding and addressing the biology is key.
  • Building an 'infrastructure of buffering' for yourself, through daily practices and supportive relationships, is crucial for healing and well-being.

Insights

1Trauma is a Biological Response, Not Just an Event

Trauma is fundamentally the body's biological reaction to overwhelming stress, not merely the stressful event itself. This distinction is crucial because the body can continue to respond in similar ways long after the event, even if the individual doesn't consciously remember it.

Dr. Burke Harris states, "At its core, trauma is the biological response to overwhelming stress... it's actually the body's reaction to that stress." She adds that experiences in infancy can shape the stress response wiring, even if the event isn't remembered: "the body remembers."

2Adverse Childhood Experiences (ACEs) Biologically Wire the Stress Response

The Adverse Childhood Experiences (ACEs) study revealed a strong dose-response relationship between childhood adversity and adult health problems. These experiences, such as abuse, neglect, or household dysfunction, can permanently alter the body's stress response, leading to increased risk for chronic diseases and mental health issues, independent of health-damaging behaviors.

The CDC and Kaiser Permanente study of 17,500 people found that ACEs were common and had a dose-response relationship with health problems. A person with four or more ACEs was significantly more likely to experience depression, substance dependence, heart disease, and chronic lung disease. 50% of this risk was directly due to the 'overactive stress response,' not just lifestyle choices.

3Buffering Re-regulates the Biological Stress Response

Buffering refers to interventions that help the body re-regulate its stress response. This includes safe, stable, and nurturing relationships, self-regulation practices (like mindfulness, exercise, time in nature), and therapeutic interventions. These actions directly inhibit the activation of the biological stress response and promote a return to balance.

Dr. Burke Harris explains that a hug releases oxytocin, which 'directly blocks the activation of the biological stress response.' She lists seven evidence-based interventions: sleep, exercise, nutrition, mindfulness, mental health, healthy relationships, and time in nature.

4Early Adversity Shifts the Body's Baseline, Requiring More Buffering

The 'teeter-totter' analogy illustrates that the younger a person experiences a stressor or trauma, the more their 'fulcrum' (baseline for stress response) shifts. This means they require significantly more buffering throughout life to balance out the impact of adversity, as their brain and body became wired to respond to stress at a highly plastic developmental stage.

Dr. Burke Harris describes how the fulcrum of a teeter-totter can shift, making the adversity side 'more pronounced and harder to balance out.' She states, 'the younger you are when you experience a stressor or trauma or adversity, you need way more buffering on the other side to be able to balance that out.'

5Willpower Fails Against a Biologically Wired Stress Response

When the stress response is overactive, the amygdala (brain's alarm system) turns down the prefrontal cortex (responsible for judgment, impulse control, executive functioning). This biological mechanism prioritizes survival over complex thought, making it difficult to 'power through' challenges with willpower alone. This can lead to shame and isolation.

Dr. Burke Harris explains that in a threat situation (like seeing a bear), the amygdala turns down the prefrontal cortex. Mel Robbins adds that trying to 'power through' this biology leads to exhaustion and self-blame, creating a 'shame layer' that further isolates individuals from needed support.

6Corrective Experiences Can Rewire Biology

The brain and body can adapt and heal through 'corrective experiences.' These are new experiences that contradict previous traumatic learnings, such as asking for help and receiving it when one previously learned help wouldn't come. Therapies like EMDR facilitate these experiences, potentially changing epigenetic markers and rewiring the stress response.

Dr. Burke Harris discusses EMDR (Eye Movement Desensitization and Reprocessing) and the importance of a 'corrective experience' where one identifies 'what should have happened.' She cites rat studies showing that buffering care changed epigenetic markers, demonstrating that 'experience of receiving buffering actually changed the epigenetic markers for these baby rats.'

Key Concepts

Trauma as Biological Response

Trauma is not merely the event that occurred, but the body's sustained biological and physiological reaction to overwhelming stress. This response can become 'wired' into the nervous system, impacting health and behavior long after the initial stressor is gone.

The Teeter-Totter Analogy (Stress & Buffering)

Imagine a teeter-totter where one side represents stress and adversity, and the other represents buffering (safe relationships, self-regulation practices). The fulcrum's position is set by early life experiences; the younger one experiences adversity, the more the fulcrum shifts, requiring significantly more buffering to maintain balance and prevent an overactive stress response.

Corrective Experiences

This model suggests that the brain and body can 'unlearn' maladaptive responses to stress through new, positive experiences that contradict previous traumatic learnings. For example, if one learned that asking for help leads to abandonment, a corrective experience would be asking for help and receiving it, thereby rewiring the nervous system.

Lessons

  • Identify your Adverse Childhood Experiences (ACEs) and acknowledge how they might be showing up in your adult life, even subtly, to begin the healing process.
  • Implement daily self-regulation practices such as mindfulness, journaling, regular exercise, spending time in nature, prioritizing sleep, and focusing on nutrition to actively buffer your biological stress response.
  • Intentionally build and nurture safe, stable, and supportive relationships in your life. Identify at least one person with whom you can be authentically vulnerable and feel safe, as connection is a key buffering mechanism.
  • Consider seeking professional support from a therapist who specializes in trauma-informed care (e.g., EMDR, trauma-focused CBT, Internal Family Systems) to process past experiences and create corrective experiences that rewire your stress response.
  • Practice 'I'm here' for yourself daily by consciously showing up with a regulated presence, acknowledging your feelings, and providing the internal safety and support you may have lacked in childhood.
  • If you love someone with an overactive stress response, be a regulated presence, witness their experience without judgment, and let them know you love them and that healing is possible.

The 7 Evidence-Based Buffering Interventions

1

Prioritize Quality Sleep: Ensure consistent, restorative sleep to support nervous system regulation.

2

Engage in Regular Exercise: Physical activity helps reduce the activity of the fight-or-flight response.

3

Maintain Healthy Nutrition: Fuel your body with nourishing foods to support overall biological balance.

4

Practice Mindfulness: Incorporate meditation or other mindfulness techniques to increase self-awareness and calm.

5

Nurture Mental Health: Seek therapy or practices that support emotional processing and well-being.

6

Cultivate Healthy Relationships: Build and lean on safe, stable, and nurturing connections with others.

7

Spend Time in Nature: Exposure to natural environments can significantly reduce stress and promote regulation.

Notable Moments

Dr. Burke Harris's personal motivation for studying trauma, stemming from her mother's untreated paranoid schizophrenia and unpredictable violence.

This personal anecdote adds profound credibility and emotional depth to her research, illustrating that even highly accomplished individuals can be shaped by ACEs and find healing through the very science they study.

Mel Robbins shares her personal experience of waking up with intense dread for three decades, unknowingly linked to a childhood sexual assault she didn't remember.

This powerful personal story from the host vividly demonstrates how the body remembers trauma even when the mind doesn't, and how an overactive stress response can manifest in adult life, validating similar experiences for listeners.

The case of a 7-year-old patient who stopped growing due to trauma, whose growth resumed with talk therapy, not hormonal treatment.

This specific clinical example highlights the profound physiological impact of trauma on a child's body and the effectiveness of psychological interventions in addressing physical symptoms rooted in an overactive stress response.

Quotes

"

"At its core, trauma is the biological response to overwhelming stress. So, a lot of us think of it as the stressor, the thing that happened to us, but it's actually the body's reaction to that stress."

Dr. Nadine Burke Harris
"

"The younger you are, those experiences that happen in infancy, they can actually shape the way that your stress response is wired. So you may not remember the actual event, but the body remembers."

Dr. Nadine Burke Harris
"

"Adversity and stress can lead to trauma in absence of adequate buffering caregiving system."

Dr. Nadine Burke Harris
"

"If you are trying to power through and you're struggling to do it because of your biology, but you don't know, you're going to say, 'Why can't I do it? Look at that guy over there. He can do it, but I can't do it. I suck.' And that's where the shame layer comes in."

Mel Robbins
"

"I believe infrastructure is love in action. What we build, the systems that we build in our personal lives for ourselves... building it ahead of time and not waiting for the wheels to fall off the cart, that would be like one of the most important things."

Dr. Nadine Burke Harris

Q&A

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